I along with searched if or not Body mass index modified the connection ranging from density and you can threat of cancer of the breast death ( Table 5)

Endurance model outcomes for new family members ranging from mammographic thickness and you may chance off breast cancer dying, stratified from the tumefaction characteristics, AJCC degree We–IV joint*

* Fully adjusted model includes covariates for AJCC stage (I, IIA, IIB, III, IV), registry (five sites), age at diagnosis (30–44, 45–49, 50–54, 55–59, 60–64, 65–69, 70–74, 75–79, ?80 years), year of diagnosis (1996–1998, 1999–2001, 2002–2003, 2004–2005), body mass index (18.5 – <25, 25 – <30, ?30kg/m 2 ), mode of detection (screen-detected, interval-detected, other screen, clinically detected, other), surgery/radiation (no breast surgery, breast conserving therapy without radiation, breast conserving therapy with radiation, other surgery), chemotherapy (yes/no), and annual median income (<$42 000, $42 000 – <$52 000, $52 000 – <$66 000, ?$66 000). Women with missing covariate information were excluded. AJCC = American Joint Committee on Cancer; BI-RADS = Breast Imaging Reporting and Data System; CI = confidence interval; ER = estrogen receptor; HR = hazard ratio; PR = progesterone receptor.

† P-value of Wald statistic to check on to possess a complete effectation of categorical BI-RADS density. All of the statistical screening was a couple-sided.

N = 96 females excluded out-of end in-specific activities

007); specifically, elevated risk associated with having almost entirely fatty breasts was apparent for obese women (BMI ?30kg/m 2 , HR = 2.02, 95% CI = 1.37 to 2.97) but not overweight (BMI 25 – <30kg/m 2 , HR = 0.70, 95% CI = 0.40 to 1.23) or lean (BMI 18.5 – <25kg/m 2 , HR = 1.27, 95% CI = 0.74 to 2.17) women. To determine whether this association was being driven by a subgroup of women who were morbidly obese (BMI ?40kg/m 2 ), we conducted post hoc analyses after excluding 313 morbidly obese women, of whom 47 died of breast cancer. In BMI-stratified results, the elevated risk associated with having almost entirely fatty breasts remained apparent for obese women (BMI 30 – <40kg/m 2 , HR = 1.68, 95% CI = 1.07 to 2.63), and the interaction between breast density and BMI was still statistically significant (P = .01).

I discover a statistically significant correspondence between Body mass index and you will BI-RADS density with respect to breast cancer passing (P to possess communications =

* BI-RADS, Nipple Imaging Revealing and Data System; Bmi, body mass index; CI, believe period; Hr, danger ratio. All cancers: Bmi ? density correspondence, P = .007.

† Fully adjusted model includes covariates for American Joint Committee on Cancer stage (I, IIA, IIB, III, IV), registry (five sites), age at diagnosis (30–44, 45–49, 50–54, 55–59, 60–64, 65–69, 70–74, 75–79, ?80 years), year of diagnosis (1996–1998, 1999–2001, 2002–2003, 2004–2005), mode of detection (screen-detected, interval-detected, other screen, clinically detected, other), surgery/radiation (no breast surgery, breast conserving therapy without radiation, breast conserving therapy with radiation, other surgery), chemotherapy (yes/no), and annual median income (<$42 000, $42 000 – <$52 000, $52 000 – <$66 000, ?$66 000). Women with missing covariate kod promocyjny farmersonly information were excluded.

‡ P worthy of out of Wald figure to check to have a total perception regarding categorical BI-RADS occurrence. Every mathematical evaluation were a couple-sided.

We located a mathematically extreme correspondence between Body mass index and you may BI-RADS occurrence in terms of cancer of the breast demise (P getting telecommunications =

* BI-RADS, Nipple Imaging Reporting and you may Study Program; Bmi, bmi; CI, depend on period; Hour, danger proportion. Every tumors: Bmi ? thickness interaction, P = .007.

† Fully adjusted model includes covariates for American Joint Committee on Cancer stage (I, IIA, IIB, III, IV), registry (five sites), age at diagnosis (30–44, 45–49, 50–54, 55–59, 60–64, 65–69, 70–74, 75–79, ?80 years), year of diagnosis (1996–1998, 1999–2001, 2002–2003, 2004–2005), mode of detection (screen-detected, interval-detected, other screen, clinically detected, other), surgery/radiation (no breast surgery, breast conserving therapy without radiation, breast conserving therapy with radiation, other surgery), chemotherapy (yes/no), and annual median income (<$42 000, $42 000 – <$52 000, $52 000 – <$66 000, ?$66 000). Women with missing covariate information were excluded.