Form ± SDs are provided getting continuous details, and percentages out of population are given to own dichotomous variables

Age-standardized functions of 86,149 ladies in new NHS We in 1994 and you will 94,715 feamales in this new NHS II within the 1995 from the quintiles from magnesium, potassium, and calcium intakes 1

Model 2 are modified for design 1 as well as consumption away from potassium and calcium (quintiles of g/d)

On the multivariate analyses, complete and you may weight reduction magnesium intakes was basically inversely regarding the likelihood of full but ischemic or hemorrhagic heart attack ( Table dos). The fresh pooled multivariate RR having complete coronary attack is 0.87 (95% CI: 0.78, 0.97; P-trend = 0.07) towards the review of females from the highest which have lowest quintiles off total magnesium intake; while the new pooled multivariate RR on the evaluation out of large with reasonable quintiles regarding weight-loss magnesium intake is actually 0.81 (95% CI: 0.69, 0.94; P-trend = 0.001) getting complete stroke. Complete potassium consumption try inversely on the threat of total however, perhaps not ischemic or hemorrhagic heart attack ( Table step 3). For analysis of women about large which have low quintiles out of complete potassium consumption, the new pooled multivariate RR to own total heart attack was 0.89 (95% CI: 0.80, 0.99; P-pattern = 0.01). Multivariate RRs both for magnesium and you may potassium was indeed attenuated whenever the step three vitamins was in fact as part of the designs likewise (multivariate design 2). There was zero high connection between full otherwise losing weight calcium consumption and you may complete, ischemic, otherwise hemorrhagic stroke ( Table 4). Multivariate RRs having full magnesium (Supplemental Table step one), full potassium (Extra Table dos), full calcium supplements (Extra Table step three), losing weight magnesium (Supplemental Desk cuatro), weight reduction potassium (Extra Dining table 5), and weightloss calcium (Supplemental Table 6) and you can risk of complete, ischemic, and you may hemorrhagic strokes for each and every cohort by themselves get on supplemental issue.

Pooled RRs (95% CIs) away from total, ischemic, and you can hemorrhagic shots because of the quintiles regarding total and you can weight reduction magnesium consumption inside the 86,149 women in the newest NHS We and you will 94,715 women in the NHS II 1

Values are the n of cases. Cox proportional hazards models were used to estimate RRs and 95% CIs. Model 1 was adjusted for age, calendar year, total calories (quintiles of kcal), BMI (in kg/m 2 ; <25, 25 to <30, or ?30), parental history of heart disease (aged ?60 y), alcohol intake (0, 0 to <5, 5 to <10, 10 to <15, or ?15 g/d), physical activity (<3, 3 to <9, 9 to<18, 18 to <27, or ?27 metabolic equivalent tasks/wk), smoking, postmenopausal hormone therapy, oral contraceptive use (never, past, or current), menopausal status (premenopausal or postmenopausal), aspirin (0 to <2 or ?2 pills/wk), multivitamin, history of hypertension, hypercholesterolemia, diabetes at baseline, and thiazide use (yes or no). NHS, Nurses' Health Study.

Pooled RRs (95% CIs) out-of complete, ischemic, and you can hemorrhagic strokes by the quintiles regarding complete and you will dietary magnesium intake inside the 86,149 ladies in the brand new NHS We and you can 94,715 women in new NHS II 1

Values are the n of cases. Cox proportional hazards models were used to estimate RRs and 95% CIs. Model 1 was adjusted for age, calendar year, total calories (quintiles of kcal), BMI (in kg/m 2 ; <25, 25 to <30, or ?30), parental history of heart disease (aged ?60 y), alcohol intake (0, 0 to <5, 5 to <10, 10 to <15, or ?15 g/d), physical activity (<3, 3 to <9, 9 to<18, 18 to <27, or ?27 metabolic equivalent tasks/wk), smoking, postmenopausal hormone therapy, oral contraceptive use (never, past, or current), menopausal status (premenopausal or postmenopausal), aspirin (0 to <2 or ?2 pills/wk), multivitamin, history of hypertension, hypercholesterolemia, diabetes at baseline, and thiazide use (yes or no). NHS, Nurses' Health Study.